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The membrane-bound folate receptor has the highest affinity for folate (Kd 0.11 nmol/l), characteristically binds folic acid, reduced folates, many antifolate drugs, and folate conjugates, and transports them by a non-classical endocytic mechanism 881,885

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PER1 expression in cells appears to sensitize cancer cells to radiation

Among the main determinants of RBC deformability (Maruyama et al., 2022), the mean corpuscular volume (MCV, as a measure of cellular size) was considered

A 28-day repeated dosing study in rats and beagle dogs at multiple doses showed no significant adverse changes compared to saline controls